ATLANTA — Delta Air Lines and Aeromexico have taken their partnership to new heights, with a move towards creating the largest transborder alliance between Mexico and the U.S.

Delta and Aeromexico, both SkyTeam alliance carriers, have been partners for 22 years. New conditional antitrust immunity granted by the U.S. Department of Transportation represents the next step in the process, announced last year, to launch a cash tender offer for Delta’s acquisition for up to 49% of Grupo Aeromexico S.A.B. de C.V., capital stock, further strengthening the partnership between the two airlines.

“Together, Delta and Aeromexico are stronger in the U.S.-Mexico market than either airline can be on its own,” said Delta CEO Ed Bastian. “The partnership will make it possible for us to offer customers more flights to more destinations, with more choices every time someone travels across the border. We will offer industry-leading reliability, great service and an unmatched array of options.”

Aeromexico CEO Andrés Conesa said the agreement “will mark the beginning of a new era in the aviation of North America … It is the next step in our relationship, and our networks will provide more benefits to our customers while increasing the options for connectivity, products and services.”

Once conditions requested by DOT and the Mexican Federal Economic Competition Commission have been fulfilled, the agreement will allow Aeromexico and Delta to coordinate efforts to enhance the travel experience with expanded destinations and frequencies, improved connecting schedules and seamless operations.

The agreement will also improve the experience on the ground, allowing the airlines to co-locate and invest in airport facilities by improving gates and lounges. The airlines also will increase joint sales and marketing initiatives.